Everyday scientists and medical doctors work together to discover possible treatments, more likely a better one, for various medical diseases. Up until now, several medical conditions remain incurable such as AIDS and Cancer. But with continuous medical study and experimentation, some experiments have shown promising results, for an instance in autoimmune diseases such as that with liposomal clodronate.
The results concerning clodronate liposome therapy has been quite fascinating. It showed a strong performance in suppressing the immune system which gave a new hope for rejected transplant patients as well as those that have been suffering on the worst stage of their autoimmune disease. Additionally, such therapy also showed positive results in conjunction with cancer drugs.
There are countless of cells that make up the immune system, macrophages however is said be the core of it. Its primary function is to activate natural immunity and regulate non-phagocytic cells. Macrophages play an important role in natural immune response and immunity, and are responsible in maintaining homeostasis by ingesting and digesting microorganism.
Inflammatory marker as the name implies is a sign that inflammation is currently going on. Famous inflammatory markers includes interleukin 6,8 and 1 as well as TNF-alfa. However, these markers are only a tiny part of the immune system. Indeed, the immune system consists of thousands of cells all of which has its own tiny role.
As a whole, the immune system is a major factor in one's health and body. It does protect one on being infected from common viruses which explains why some people take supplementation to strengthen their immune system. But for some unique reason, the immune system could be the culprit to several medical diseases as well as on transplant rejections.
Autoimmune diseases are medical conditions caused by the immune system itself. Macrophages, the core cell of the immune system, attack healthy cells causing inflammation such as those in multiple sclerosis, pernicious anemia, rheumatoid arthritis and so on. During transplant, macrophages may also attack the new cells coming from the graft causing the body to reject it.
Using the liposomes as a drug vehicle, clodronic acid will be delivered into your phagocytic cell, or macrophages damaging it irreversibly then kills it eventually through apoptosis. Aptly name as the macrophage "suicide'', this will result to a decreased or minimal immune reaction hence patients with autoimmune disease may show improvement from their condition.
With the discovery of clodronic acid therapy, these possibilities may be the least of your concerns. Through the use of liposomes as the drug vehicle the main drug, clodronic acid will be delivered inside the macrophages and after exceeding its threshold, dies by apoptosis. Liposomes are easily engulfed by macrophages which makes it a great choice as a drug vehicle. As the drug is delivered directly into the phagocytic cells, there's a greater chance of suppressing the immune system.
Liposomal clodronate showed exemplary results in autoimmune diseases, transplant and cancer. It would not be much of a surprise if it becomes the next big thing in medicine. That is, if it's still not considered one until now.
The results concerning clodronate liposome therapy has been quite fascinating. It showed a strong performance in suppressing the immune system which gave a new hope for rejected transplant patients as well as those that have been suffering on the worst stage of their autoimmune disease. Additionally, such therapy also showed positive results in conjunction with cancer drugs.
There are countless of cells that make up the immune system, macrophages however is said be the core of it. Its primary function is to activate natural immunity and regulate non-phagocytic cells. Macrophages play an important role in natural immune response and immunity, and are responsible in maintaining homeostasis by ingesting and digesting microorganism.
Inflammatory marker as the name implies is a sign that inflammation is currently going on. Famous inflammatory markers includes interleukin 6,8 and 1 as well as TNF-alfa. However, these markers are only a tiny part of the immune system. Indeed, the immune system consists of thousands of cells all of which has its own tiny role.
As a whole, the immune system is a major factor in one's health and body. It does protect one on being infected from common viruses which explains why some people take supplementation to strengthen their immune system. But for some unique reason, the immune system could be the culprit to several medical diseases as well as on transplant rejections.
Autoimmune diseases are medical conditions caused by the immune system itself. Macrophages, the core cell of the immune system, attack healthy cells causing inflammation such as those in multiple sclerosis, pernicious anemia, rheumatoid arthritis and so on. During transplant, macrophages may also attack the new cells coming from the graft causing the body to reject it.
Using the liposomes as a drug vehicle, clodronic acid will be delivered into your phagocytic cell, or macrophages damaging it irreversibly then kills it eventually through apoptosis. Aptly name as the macrophage "suicide'', this will result to a decreased or minimal immune reaction hence patients with autoimmune disease may show improvement from their condition.
With the discovery of clodronic acid therapy, these possibilities may be the least of your concerns. Through the use of liposomes as the drug vehicle the main drug, clodronic acid will be delivered inside the macrophages and after exceeding its threshold, dies by apoptosis. Liposomes are easily engulfed by macrophages which makes it a great choice as a drug vehicle. As the drug is delivered directly into the phagocytic cells, there's a greater chance of suppressing the immune system.
Liposomal clodronate showed exemplary results in autoimmune diseases, transplant and cancer. It would not be much of a surprise if it becomes the next big thing in medicine. That is, if it's still not considered one until now.
About the Author:
When you need the best source for high quality liposomal clodronate, click the link to www.clodrosome.com. For more details on Encapsula NanoSciences. Visit us at http://www.clodrosome.com today.
No comments:
Post a Comment